May 11, 2007· 2.1. Inbred mice. Several inbred mouse species (BALB/c, C57BL/6 (B6), 129S) have been shown to support SARS-CoV replication and to demonstrate pneumonitis (129S) and clinical signs of SARS disease (aged BALB/c) (Glass et al., 2004, Hogan et al., 2004, Roberts et al., 2005a, Subbarao et al., 2004).The inbred mouse model has several advantages including small size, cost, availability in …